Antioxidant Activity of Panax ginseng to Regulate ROS in Various Chronic Diseases

Reactive oxygen species (ROS)-the byproduct of regular cell activity formed by various cellular components—play a significant role in pathological and physiological conditions. Alternatively, antioxidants are compounds that reduce or scavenge reactive cells. An asymmetry between the antioxidant defense system ROS from intracellular extracellular sources cause chronic diseases such as cancer, inflammation, tumorigenesis, cardiovascular neurogenerative diseases. However, Panax ginseng its secondary metabolites (known ginsenosides, phenolic compounds, peptides, acid polysaccharides, polyacetylene, alkaloids) well-recognized many vitro vivo experiments which show beneficial regulating these There extensive evidences P. can destroy cancer cells specifically increasing oxidative stress through generation without significantly harming normal Additionally, numerous studies have examined derivatives on ROS-mediated signaling pathways discussed herein. This review summarizes potential several diseases, gives updated research evidence with related mechanisms future possibilities nano-formulated other polyphenols.